Modified bacterial surface layer proteins
CA 2471916 A1 · Owner: Nederlandse Organisatie Voor Toegepastnatuurwetenschappelijk Onderzoek Tno · Inventors: Smit, Egbert; Pouwels, Pieter Hendrik; Tielen, Frans
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Modified bacterial surface layer (S-layer) proteins are disclosed where the modification is the insertion, at an internal location of a heterologous , polypeptide, or polypeptide of interest. The polypeptide is a binding or target protein, such as an antigen or antibody or part thereof, in particular , a bacterial antigen (e.g. from Clostridium tetani such as TTFC). The modified surface layer protein can then be expressed on the surface of the bacterial cell and used in a vaccine. Also disclosed are bacteria which have been modified to express a heterologous surface layer protein but which do not as , a wild-type possess an S-layer (such as L. casei) and modified bacteria which , …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 23, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 23, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 23, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.