Methods of generating multispecific, multivalent agents from vh and vl domains
CA 2471868 A1 · Owner: Ibc Pharmaceuticals · Inventors: Chang, Chien-Hsing Ken; Rossi, Edmund; Goldenberg, David
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
This invention relates to multi-specific multivalent binding proteins and , methods of generating these agents from VH and VL domains. The binding protein has three or more binding sites where at least one binding site binds with a hapten moiety and at least two sites bind with target antigens. The present invention further relates to bispecific trivalent heterodimers that have at , least one binding site with affinity towards molecules containing a histaminesuccinyl-glycyl (HSG) moiety and at least two binding sites with affinity towards carcinoembryonic antigen (CEA) and to trispecific, trivalent , heterodimers that have at least one binding site with affinity towards molecules …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 26, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 26, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 26, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.