Plasmid mediated supplementation for treating chronically ill subjects

Abstract From the Canadian patent

The present invention pertains to compositions and methods for plasmidmediated supplementation. The compositions and method are useful for retarding the growth of the tumor, and retarding cachexia wasting, anemia and other , effects that are commonly associated in cancer bearing animals. Overall the , embodiments of the invention can be accomplished by delivering an effective amount of a nucleic acid expression construct that encodes a GHRH or functional biological equivalent thereof into a tissue of an animal and allowing expression of the encoded gene in the animal. For example when such , a nucleic acid sequence is delivered into the specific cells of the animal tissue specific …