Assay for screening candidate drugs for the treatment of inflammatory diseases
CA 2468082 C · Owner: Rowett Research Institute · Inventors: Kelly, Denise
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to an assay to select a candidate drug for the treatment of inflammatory disease due to cytokine production. The assay comprises: a) exposing said candidate drug to intestinal cells; and b) analysing the effect of the said candidate drug selected from the group consisting of the variation of nuclear export or import of transcription factors from the NF-.kappa.B family the disruption of transcriptional activity of transcription factors from the NF-.kappa.B family, the differential histone acetylation of p65 (RelA); the variation of the amount of PPAR.gamma./RelA complexes in the cytosol of the cells; and the variation in the levels of one or more cytokines. The …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed November 20, 2002 and granted June 26, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended November 20, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 20, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.