Methods of expressing lim mineralization protein in non-osseous cells
CA 2466769 A1 · Owner: Sdgi Holdings, Inc. · Inventors: Yoon, Sangwook T.; Mckay, William F.; Boden, Scott D.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Methods of expressing LIM mineralization protein in non-osseous mammalian cells, such as stem cells or intervertebral disc cells (e.g. cells of the annulus fibrosus, or cells of the nucleus pulposus) are described. The methods involve transfecting the cells with an isolated nucleic acid comprising a nucleotide sequence encoding a LIM mineralization protein operably linked to a promoter. Transfection may be accomplished ex vivo or in vivo by direct injection of virus or naked DNA, or by a nonviral vector such as a plasmid. Expression of the LIM mineralization protein can stimulate proteoglycan and/or collagen production in cells capable of producing proteoglycyan and/or collagen. …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed November 14, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended November 14, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 14, 2024.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.