Isolated peptide of the hepatocyte growth factor and its variants, preparation method and therapeutic use as anti-angiogenic agents
CA 2465714 A1 · Owner: Institut Des Vaisseaux Et Du Sang · Inventors: Merkoulova-Rainon, Tatiana
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention concerns a peptide substance selected from the group consisting of: (i) peptide N derived from the HGF .alpha. chain and having an amino acid sequence represented by SEQ ID No. 2 and (ii) its peptide variants derived from said peptide N sequence by suppression substitution or addition of one or several amino acids. Said peptide N has an anti-angiogenic activity in accordance with a mechanism different from competitive fixation with HGF on the HGF-R receptor. The invention also concerns the therapeutic use and the preparation method of said peptide substance as well as (i) the DNA fragment which expresses it the plasmid containing said DNA and the bacteria containing said …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed October 30, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended October 30, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 30, 2024.
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.