4piperidin-4-yliden-(3-carbamoylphenyl)methyl benzamide derivatives and their use for the treatment of pain, spinal injuries or gastrointestinal disorders

Abstract From the Canadian patent

Compounds of general formula (I) wherein R1 is selected from any one of phenyl, pyridinyl, thienyl, furanyl, imidazolyl pyrrolyl and triazolyl; where , each R1 phenyl ring and R1 heteroaromatic ring may optionally and independently be further substituted by 1 2 or 3 substituents selected from , straight and branched C1-C6 alkyl NO2, CF3, C1-C6 alkoxy, chloro, fluoro bromo, and iodo. The substitutions on thephenyl ring and on the heteroaromatic ring may take place in any position on said ring systems; are disclosed and claimed in the present application, as well as their pharmaceutically acceptable salts and pharmaceutical compositions comprising the novel compounds and their use in …