Method and composition for treating immune complex associated disorders
CA 2459310 A1 · Owner: The Trustees Of Boston University · Inventors: Marshak-Rothstein, Ann; Leadbetter, Elizabeth; Rifkin, Ian
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides methods and compositions for treating immune complex associated diseases (ICAD), such as SLE rheumatoid arthritis, and , hepatitis-C related immune complex disease (e.g. cryoglobulinemia) in a subject having an ICAD or at risk for developing ICAD. The invention is based upon the surprising finding that chromatin-containing immune complexes activate autoreactive B cells and dendritic cells by a dual receptor engagement process which, in both cell types involves a Toll-like receptor , (TLR). The methods of treating ICAD comprise administering a compound to an individual in need thereof that either 1) inhibits formation of the immune complex either by …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 9, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended September 9, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 9, 2024.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.