Regulation of cytotrophoblast cell differentiation and cell migration
CA 2458972 A1 · Owner: Adelaide Research & Innovation Pty Ltd · Inventors: Roberts, Claire; Owens, Phillip
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention is predicated on the discovery of certain interactions between cellular growth factors and opposing actions that control differentiation and migration or invasion of cytotrophoblasts into the uterine endometrium during pregnancy. IGF-II and latent transforming growth factor beta (TGF.beta.), the inactive precursor of TGF.beta. complete for binding to the CIM6P receptor. IGF-II prevents latent TGF.beta. binding to the CIM6P receptor. The invention therefore offers a method of regulating and directing cytotrophoblast differentiation and function based on the interaction between IGF-II, latent TGF.beta. and the CIM6P receptor. There is disclosed a method of …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed August 30, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended August 30, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 30, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.