Novel method for synthesis of (2s, 3as, 7as)-1-(s)-alanyl-octahydro-1h-indole-2-carboxylic acid derivatives and use for synthesis of perindopril
CA 2455706 C · Owner: Les Laboratoires Servier · Inventors: Porcs-Makkay, Marta; Simig, Gyula; Mezei, Tibor
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention concerns a method for industrial synthesis of compounds of formula (I) wherein: R¿1? represents a hydrogen atom or a linear or branched C¿1?-C¿6? alkyl group or benzyl and R¿2? represents a group protecting the amino function. The invention also concerns the use of same for industrial synthesis of perindopril of formula (II) and its pharmaceutically acceptable salts.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 23, 2002 and granted January 24, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended July 23, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 23, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.