Protein kinase inhibitors comprising atp mimetics conjugated to peptides or peptidomimetics
CA 2455602 A1 · Owner: Senderowitz, Hanoch · Inventors: Senderowitz, Hanoch; Ohne, Onsat; Livnah, Nurit
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides small molecules having high affinity to the ATP binding site of protein kinases, which are conjugated to apeptide or peptidomimetic moiety which mimics the substrate of PKB. The chimeric compounds according to the present invention preferably serve as PKB inhibitors with improved activity and selectivity. Novel ATP mimetic compounds particularly isoquinoline derivatives, conjugated with peptides or peptidomimetics are useful as inhibitors of protein kinases for experimental medical, and drug design purposes. Furthermore pharmaceutical compositions , comprising these protein kinase inhibitors and methods of using such , compositions for treatment and …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 25, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended July 25, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 25, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.