Methods and devices based upon a novel form of nucleic acid duplex on a surface
CA 2453524 A1 · Owner: Belosludtsev, Yuri · Inventors: Powdrill, Tom; Belosludtsev, Yuri; Lemeshko, Sergy
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to simple method to fabricate DNA hybridization devices based upon adsorptive attachment of oligonucleotides to a positively charged surface. Such adsorbed oligonucleotide probes form a densely packed monolayer, which retains capacity for base-pair specific hybridization with a solution state nucleic acid target strand to form the duplex. However both , strand dissociation kinetics and the rate of DNase digestion suggest on symmetry grounds that solution-state nucleic acid binds to such adsorbed oligonucleotides to form a highly asymmetric and unwound duplex with , structural details that are substantially different from that known for the Watson-Crick …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 11, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended July 11, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 11, 2024.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.