Methods of inhibiting amyloid toxicity
CA 2453403 C · Owner: Prenner, Irene Griswald · Inventors: Prenner, Irene Griswald; Wright, Sarah; Yednock, Theodore
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides methods and compositions for inhibiting amyloidogenic , protein toxicity, inhibiting formation of an amyloidogenic protein deposit and/or treating , amyloidogenic diseases by administering a pharmaceutically effective amount of one or more , agents that specifically bind: a) an integrin subunit, wherein the integrin subunit is .alpha.2 .alpha.v, .alpha.6, or .beta.1;, b) an integrin wherein the integrin is .alpha.2.beta.1 .alpha.6.beta.1, or , .alpha.v.beta.1; or c) laminin;, wherein, the agents are chosen from: (i) fibronectin; (ii) superfibronectin; and (iii) an , antagonistic or blocking antibody or a fragment thereof.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 8, 2002 and granted October 8, 2013. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended July 8, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 8, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.