T cell regulatory genes and methods of use thereof
CA 2452196 A1 · Owner: Dana-Farber Cancer Institute, Inc. · Inventors: Umetsu, Dale T.; Freeman, Gordon J.; Mcintire, Jennifer Jones
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A genetic locus and corresponding family of proteins associated with regulation of immune function and cell survival are provided. These genes encode cell surface molecules with conserved IgV and mucin domains. The locus comprising the TIM family is genetically associated with immune dysfunction including asthma. Furthermore, the TIM gene family is located within a region of human chromosome 5 that is commonly deleted in malignancies and myelodysplastic syndrome. Polymorphisms in the gene sequences are associated with the development of airway hyperreactivity and allergic inflammation and , T cell production of IL-4 and IL-13. The proteins include the human hepatitis A cellular …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 1, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended July 1, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 1, 2024.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.