Method of determining a chemotherapeutic regimen based on glutathione-s-transferase pi expression
CA 2450257 C · Owner: Danenberg, Kathleen D. · Inventors: Danenberg, Kathleen D.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing GST -pi expression levels in fixed or fixed and paraffin embedded tissues and prognosticate the probable resistance or sensitivity of a patient's tumor to treatment with platinum-based therapies by examination of the amount of GST -pi mRNA in a patient's tumor cells and comparing it to a predetermined threshold expression level. More specifically the invention provides to oligonucleotide primer pair GST-piand methods comprising their use for detecting levels of GST-pi mRNA.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 15, 2002 and granted November 6, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended May 15, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 15, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.