Novel method for cloning variable domain sequences of immunological gene repertoire
CA 2450217 A1 · Owner: Ji, Henry Hongjun · Inventors: Ji, Henry Hongjun
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to a non-PCR (polymerase chain reaction) process, particularly a transcription-based amplification method for , amplifying and cloning sequences containing a variable domain sequence such as an immunoglobulin variable domain sequence from the immunological gene repertoire. The present invention comtemplates the expression of antibody library in either in an in vivo expression vector or in an in vitro transcription/translation system. Isolation of a gene coding for a receptor having the ability to bind a preselected ligand and receptors produced by the gene isolated by the method is also contemplated.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 14, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 14, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 14, 2024.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.