Mutant forms of cholera holotoxin as an adjuvant
CA 2449670 A1 · Owner: Green, Bruce A. · Inventors: Jobling, Michael G.; Zhu, Duzhang; Holmes, Randall K.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Mutant cholera holotoxins having single or double amino acid substitutions or insertions have reduced toxicity compared to the wild-type cholera holotoxin. The mutant cholera holotoxins are useful as adjuvants in antigenic compositions to enhance the immune response in a vertebrate host to a selected antigen from a pathogenic bacterium, virus fungus, or parasite, a cancer , cell, a tumor cell an allergen, or a self-molecule.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 5, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended June 5, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 5, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.