Preparation of 17-phenyl- 18, 19, 20- trinor-pgf2.alpha. and its derivatives
CA 2448631 A1 · Owner: Gutman, Arie L. · Inventors: Etinger, Marina; Yudovitch, Lev; Gutman, Arie L.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides a new and effective process for the synthesis of 17-phenyl-18,19,20-trinor-PGF2.alpha. and its derivatives including the , anti-glaucoma drugs Bimatoprost and Latanoprost. The benefit of the present invention rises inter alia from the fact that a major intermediate involved in the synthesis of the above compounds may be isolated from a mixture containing also an undesired isomer, by crystallization. In addition the undesired , isomer may be oxidized to give the starting compound which is then recycled.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 30, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 30, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 30, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.