Inhibitors of receptor activator of nf-kb and uses thereof
CA 2447431 A1 · Owner: Aggarwal, Bharat · Inventors: Darnay, Bryant G.; Singh, Sujay; Aggarwal, Bharat
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides a RANK (receptor activator of NF-.kappa.B) inhibitor consisted of a TRAF-6 (TNF receptor-associated factor-6) binding domain attached to a leader sequence. The peptide inhibitor inhibits RANKL (RANK ligand)-mediated osteoclast differentiation thus indicating that , targeted disruption of interaction between RANK and TRAF6 may prove useful as a therapeutic for metabolic bone disorders leukemia, arthritis, and , metastatic cancer of the bone.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 10, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 10, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 10, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.