4-(phenyl-piperidin-4-ylidene-methyl)-benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders

Abstract From the Canadian patent

Compounds of general formula I R1 is selected from any one of phenyl pyridinyl, pyrrolyl, thienyl, furanyl, imidazolyl triazolyl, thiazolyl, and , pyridine N-oxide; where each R1 phenyl ring and R1 heteroaromatic ring may optionally and independently be further substituted by 1 2 or 3 substituents , selected from straight and branched C1-C6 alkyl NO2, CF3, C1-C6 alkoxy, chloro, fluoro bromo, and iodo. The substitutions on the phenyl ring and on the heteroaromatic ring may take place in any position on said ring systems;are disclosed and claimed in the present application as well as salts , and pharmaceutical compositions comprising the novel compounds and their use in therapy, in …