A high throughput assay for identification of gene expression modifiers
CA 2446207 A1 · Owner: Health Research, Inc. · Inventors: Hangauer, David G.; Stewart, Carleton C.; Mielnicki, Lawrence Mark
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides a method for screening of a large number of compounds for their ability to modulate the expression of genes. The method uses gene trap technology and comprises the steps of transfecting a population of cells with a gene-trap vector, sorting cells according to their level of fluorescence, distributing sorted cells into pools and expanding the pools to obtain a sufficient number of cells representing each trapped gene to permit distinction of the effect of a test compound over controls exposing the cells , to the test compounds and identifying compounds which alter the fluorescence distribution pattern of cells using FACS analysis.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 6, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 6, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 6, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.