N-biphenylcarbonyl- and n-phenylpyridylcarbonyl substituted bi- and tricyclic azepines and diazepines as vasopressing agonists

Abstract From the Canadian patent

A compound of the formulae (I) or (II): wherein Y is a moiety selected from NR or -(CH2)n; wherein R is hydrogen or (C1-C6) lower alkyl and n is 1; (Z), represents; (1) a phenyl ring optionally substituted with one or two substituents selected, independently, from the group comprising hydrogen (C1-, C6) lower alkyl, halogen, cyano, CF3 hydroxy, (C1-C6) lower alkoxy, (C1-C6) lower alkoxy carbonyl, carboxy, -CONH2 -CONH(C1-C6)lower alkyl, -CON(C1-, C6)lower alkyl2; or (2) a 6-membered aromatic (unsaturated) heterocyclic ring having one nitrogen atom, optionally substituted by (C1-C6) lower alkyl halogen or (C1-C6) lower alkoxy; (W), represents: (1) a phenyl ring optionally substituted …