Isolation of dna molecules using mercapto-aryl ligands
CA 2444259 C · Owner: Ge Healthcare Bio-Sciences Ab · Inventors: Berglof, Jan; Nyhammar, Tomas; Lemmens, Raf
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to a process for separating nucleic acid molecules, preferably open circular and supercoiled plasmid DNA and RNA molecules from each other, comprising the steps of providing a solution comprising the molecules; adsorbing the molecules to adsorbing groups on a carrier; and optionally washing the column with a suitable solution. The present process is especially suitable for large-scale isolation of supercoiled ccc DNA to be used in gene therapy.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 15, 2002 and granted October 2, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended April 15, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 15, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.