Intermediates and enzymes of the non-mevalonate isoprenoid pathway
CA 2443874 A1 · Owner: Hecht, Stefan · Inventors: Hecht, Stefan; Eisenreich, Wolfgang; Rohdich, Felix
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention provides a protein in a form that is functional for the enzymatic conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate to 1hydroxy-2-methyl-2-butenyl 4-diphosphate notably in its (E)-form of the nonmevalonate biosynthetic pathway to isoprenoids. The invention also provides a protein in a form that is functional for the enzymatic conversion of 1-hydroxy- 2-methyl-2butenyl 4-diphosphate, notably in its (E)-form to isopentenyl , diphosphate and/or dimethylallyl diphosphate. Further screening methods for , inhibitors of these proteins are provided. Further 1-hydroxy-2-methyl-2-, butenyl 4-diphosphate is provided and chemical and enzymatic methods of its preparation.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 10, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended April 10, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 10, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.