Process for producing nerve stem cells, motor neurons, and gabaergic neurons from embryonic stem cells
CA 2443151 C · Owner: Okano, Hideyuki · Inventors: Okano, Hideyuki; Shimazaki, Takuya
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A process for producing motor neurons and GABAergic neurons characterized by comprising suspension-culturing embryonic stem cells in the presence or absence of a protein noggin to form embryoids deriving the embryoids into , nerve stem cells by suspension culture in the presence of a fibroblast growth factor and a sonic hedgehog protein, and then differentiating the same. According to this method, at least motor neurons and GABAergic neurons can be systematically and efficiently produced from ES cells. Selective acquisition of neurons would be applicable to the transplant therapy for amyotrophic lateral sclerosis, Huntington's chorea Alzheimer's disease, etc.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed October 3, 2001 and granted June 7, 2011. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended October 3, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 3, 2023.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.