Indolinones substituted in the 6-position, the preparation thereof and their use as medicaments
CA 2442695 A1 · Owner: Van Meel, Jacobus · Inventors: Hilberg, Frank; Heckel, Armin; Van Meel, Jacobus
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to indolinones, substituted in position 6 of general , formula (I), in which R1 to R5 and X are defined as per claim (1). The invention also relates to their isomers and salts in particular to their , physiologically compatible salts which have valuable pharmacological , properties specifically an inhibiting action on various receptor tyrosine kinases and cyclin/CDK complexes, in addition to on the proliferation of endothelium cells and various tumour cells. The invention further relates to medicaments containing said compounds, to the use of said medicaments and to a method for their production.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 30, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 30, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 30, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.