Novel mhc molecule constructs, and methods of employing these constructs for diagnosis and therapy, and uses of mhc molecules

Abstract From the Canadian patent

Novel compounds carrying ligands capable of ligating to counter receptors on relevant target cells are disclosed. The compounds possess a number of advantageous features, rendering them very suitable for a wide range of applications, including use as detection systems detection of relevant target , cells as well as in various methods. In particular novel MHC molecule , constructs comprising one or more MHC molecules are disclosed. The affinity and avidity of the MHC molecules of the constructs are surprisingly high. The possibility of presenting to the target cells a plurality of MHC molecules makes the MHC molecule constructs an extremely powerful tool e.g. in the field of …