Novel approach to design glycopeptides based on o-specific polysaccharide of shigella flexneri serotype 2a
CA 2434668 A1 · Owner: Phalipon, Armelle · Inventors: Grandjean, Cyrille; Phalipon, Armelle; Baleux, Francoise
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
As part of a program for the development of synthetic vaccines against the pathogen, Shigella flexneri, the conformational behavior of the O-specific polysaccharide (O-SP) of S. flexneri 5a and of four related synthetic pentasaccharide fragments was studied with a, combination of NMR and molecular modeling methods. The NMR conformational analysis based, on 1H and 13C chemical shifts analysis inter-residue distances evaluation as well as one- and, three-bond heteronuclear coupling constants measurements shows that the conformation of one of, the four related pentasaccharides closely mimics the conformational features of the native O-SP, in solution. Inhibition ELISA demonstrated that …
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 7, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended July 7, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 7, 2025.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.