Binding domain-immunoglobulin fusion proteins
CA 2433877 C · Owner: Aptevo Research And Development Llc · Inventors: Hayden-Ledbetter, Martha; Ledbetter, Jeffrey A.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to novel binding domain-immunoglobulin fusion proteins that feature a binding domain for a cognate structure such as an antigen a , counterreceptor or the like, a hinge region polypeptide having either zero or one cysteine residue, and immunoglobulin CH2 and CH3 domains and that are , capable of ADCC and/or CDC while occurring predominantly as monomeric polypeptides. The fusion proteins can be recombinantly produced at high expression levels. Also provided are related compositions and methods including immunotherapeutic applications.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 17, 2002 and granted November 18, 2014. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended January 17, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 17, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.