Method for producing alpha-hydroxy acid, glycolic acid 2-hydroxyisobutyric acid from a corresponding alpha-hydroxy nitrile using nitrilase
CA 2433036 A1 · Owner: Gavagan, John E. · Inventors: Gavagan, John E.; Dicosimo, Robert; Fall0N, Robert D.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to a method for producing .alpha.-hydroxy acids from the corresponding .alpha.-hydroxy nitrile using a catalyst having nitrilase activity. More specifically, the invention pertains to use of Acidovorax facilis 72W (ATCC 55746) nitrilase to hydrolyze glycolonitrile to glycolic acid, or acetone cyanohydrin to 2-hydroxyisobutyric acid. Glycolonitrile is reacted in an aqueous mixture with a catalyst having Acidovorax facilis 72W nitrilase activity to give glycolic acid selectively and at high concentration and high yield.-hydroxy nitrile using a catalyst having nitrilase activity. More specifically the invention pertains to use of , Acidovorax facilis 72W …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed February 20, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended February 20, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by February 20, 2024.
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Timeline
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.