Feedback-resistant pyruvate carboxylase gene from corynebacterium
CA 2425754 C · Owner: Sinskey, Anthony · Inventors: Hanke, Paul D.; Willis, Laura B.; Guillouet, Stephane
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to a mutated pyruvate carboxylase gene from Corynebacterium. The mutant pyruvate carboxylase gene encodes a pyruvate carboxylase enzyme which is resistant to feedback inhibition from aspartic acid. The present invention also relates to a method of replacing the wildtype pyruvate carboxylase gene in Corynebacterium with this feedback-resistant pyruvate carboxylase gene. The present invention further relates to methods of the production of amino acids, preferably lysine comprising the use of this , mutant pyruvate carboxylase enzyme in microorganisms.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed October 12, 2001 and granted February 18, 2014. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended October 12, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 12, 2023.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.