Methods of high-throughput screening for internalizing antibodies
CA 2425602 C · Owner: Marks, James D. · Inventors: Marks, James D.; Nielsen, Ulrik B.; Kirpotin, Dmitri B.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
This invention provides methods of identifying ligands that are internalized into a cell. The methods typically involve (i) contacting the cell with a reporter non-covalently coupled to a ligand; (ii) dissociating the reporter from the ligand and removing dissociated reporter from the surface of the cell; and (iii) detecting the reporter within said cell (if any is present) where the presence of the reporter within said cell indicates that the ligand binds to an internalizing receptor and is internalized.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed October 17, 2001 and granted June 26, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended October 17, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 17, 2023.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.