Methods and compositions relating to muscle specific sarcomeric calcineurin-binding proteins (calsarcins)
CA 2425396 A1 · Owner: Olson, Eric N. · Inventors: Olson, Eric N.; Frey, Norbert
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to the polypeptides known as calcineurin associated protein (calsarcin). Calsarcins-1 -2, and 3 bind to calcineurin, telethonin and .alpha.-actinin, which provides a link between these molecules and the sarcomere. Sarcomeric dysfunction ultimately leads to activation of calcineurin and consequent hypertrophic cardiomyopathy. Thus methods , utilizing calsarcin as it regards these medical conditions are herein provided and include screening for peptides which interact with calsarcin screening , for modulators of calsarcin binding to calcineurin or .alpha.-actinin methods , to modulate calcineurin activity methods to inhibit calcineurin activation of gene …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed November 7, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended November 7, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 7, 2023.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.