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Method for the detection of cytosine methylations

CA 2425366 A1 · Owner: Berlin, Kurt · Inventors: Berlin, Kurt

CIPO record

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Abstract From the Canadian patent

A method for the detection of cytosine methylations in genomic DNA is disclosed, whereby genomic DNA samples are firstly reacted with a chemical reagent, whereupon 5-methylcytosine and cytosine react differently and thus display a different base pair relationship in the DNA duplex after said reaction. The pre-treated DNA is then amplified by means of a polymerase and at least one primer oligonucleotide and the amplified material once again reacted with a chemical reagent as above. The cytosine bases and/or guanine bases remaining in the amplified material after the renewed chemical treatment are detected in the final step.

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed October 10, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended October 10, 2021.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 10, 2023.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledOctober 10, 2001
GrantedNo grant recorded
Term endedOctober 10, 2021
Patent numberCA 2425366 A1
Classification (IPC)C12Q1/68

Timeline

Timeline From CIPO dates

2002200420062008201020122014201620182020Application filedOct 10, 2001Term endedOct 10, 2021

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.