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Dynamic resolution of isomers and resolved isomers

CA 2424280 A1 · Owner: Randazzo, Michael E. · Inventors: Rosso, Victor W.; Randazzo, Michael E.; Zhu, Jingyang

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Abstract From the Canadian patent

Provided is a dynamic resolution method of enriching a desired isomer of an alpha-substituted carboxylic acid relative to an undesired isomer the method , comprising: (a) in a solvent contacting the alpha-substituted carboxylic acid, wherein the alpha substitution is with a leaving group and wherein the alpha carbon is chiral, with a homochiral amine to form a salt that is partially insoluble under selected reaction conditions wherein the homochiral , amine is selected so that the solubility of the amine salt of the undesired alpha-substituted carboxylic acid is greater than that of the amine salt of the desired alpha-substituted carboxylic acid under the selected reaction …

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed September 24, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended September 24, 2021.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 24, 2023.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledSeptember 24, 2001
GrantedNo grant recorded
Term endedSeptember 24, 2021
Patent numberCA 2424280 A1
Classification (IPC)C07C213/08 +2 more

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2002200420062008201020122014201620182020Application filedSep 24, 2001Term endedSep 24, 2021

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.