Carbamic acid compounds comprising an amide linkage as hdac inhibitors
CA 2423868 C · Owner: Andrianov, Victor · Inventors: Lolya, Daina; Kalvinsh, Ivars; Harris, C. John,
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
This invention pertains to certain active carbamic acid compounds which inhibit HDAC activity and which have the following formula:, (see above formula) wherein: A is an aryl group; Q1 is an aryl leader group having a backbone of at least 2 carbon atoms; J is an amide linkage selected from: -NR1C (=O) - and -C (=O) NR1-; R1 is an amido substituent; and, Q2 is an acid leader group; and pharmaceutically acceptable salts, solvates amides, esters, and ethers, thereof. The present invention also pertains to pharmaceutical compositions comprising such compounds and , the use of such compounds and compositions both in vitro , and in vivo, to inhibit HDAC and to inhibit conditions such , as …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 27, 2001 and granted June 7, 2011. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended September 27, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 27, 2023.
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