Hydroxamic acid compounds comprising a sulfonamide linkage as hdac inhibitors
CA 2423744 C · Owner: Moore, Kathryn G. · Inventors: Vorona, Maxim; Andrianov, Victor; Starchenkov, Igor
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
This invention pertains to certain active hydroxamic acid compounds which inhibit HDAC activity and which have the following formula: (I) A is an aryl , group; Q1 is a covalent bond or an aryl leader group; J is a sulfonamide linkage , selected from: -S(=O)2NR1- and -NR1S(=O)2-; R1 is a sulfonamido substituent; and, Q2 is an acid leader group; with the proviso that if J is -S(=O)2NR1then Q1 , is an aryl , leader group; and pharmaceutically acceptable salts solvates, amides, esters, ethers, chemically protected forms and prodrugs thereof. The present , invention also pertains to pharmaceutical compositions comprising such compounds and the use , of , such compounds and compositions both …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 27, 2001 and granted April 3, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended September 27, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 27, 2023.
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