Co-crystal structure of monoclonal antibody 5c8 and cd154, and use thereof in drug design
CA 2421055 A1 · Owner: Taylor, Frederick R. · Inventors: Zheng, Zhongli; Karpusas, Michael; Taylor, Frederick R.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to compositions and crystals of CD154 (CD40L) in complex with an anti-CD154 antibody. In addition this invention relates to , the high resolution structure of a CD154/anti-CD154 antibody complex as obtained by X-ray crystallography. Specifically this structure provides , binding sites defined by the structure coordinates determined herein. This invention also relates to a computer (machine) comprising a machine-readable data storage medium comprising a data storage material encoded with machinereadable data comprising the structure coordinates provided by this invention. The computer has instructions to process said machine-readable data into a …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed August 31, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended August 31, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 31, 2023.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.