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Methods of treatment of a bcl-2 disorder using bcl-2 antisense oligomers

CA 2419480 A1 · Owner: Klem, Robert E. · Inventors: Fingert, Howard; Warrel, Raymond P. Jr.; Klem, Robert E.

CIPO record

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Abstract From the Canadian patent

The present invention is directed to the use of bcl-2 antisense oligomers to treat and prevent bcl-2 related disorders. These disorders include cancers tumors, carcinomas and cell-proliferative related disorders. In one embodiment of the invention, a bcl-2 antisense oligomer is administered at high doses. The present invention is also directed to a method of preventing or treating a bcl-2 related disorder, in particular cancer comprising administering a bcl-2 , antisense oligomer for short periods of time. The present invention is further drawn to the use of bcl-2 antisense oligomers to increase the sensitivity of a subject to cancer therapeutics. The present invention also relates to …

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed August 23, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended August 23, 2021.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 23, 2023.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledAugust 23, 2001
GrantedNo grant recorded
Term endedAugust 23, 2021
Patent numberCA 2419480 A1
Classification (IPC)A61K48/00 +2 more

Timeline

Timeline From CIPO dates

2002200420062008201020122014201620182020Application filedAug 23, 2001Term endedAug 23, 2021

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.