Modulation of a.beta. levels by .beta.-secretase bace2
CA 2413209 A1 · Owner: Liu, Yu-Wang · Inventors: Liu, Yu-Wang; Quon, Diana Hom; Cordell, Barbara
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention is based on the findings that BACE2 a homolog of .beta.-, secretase BACE, is able to stimulate processing of APP in a non-amyloidogenic pathway, thereby suppressing the level of A.beta.. Accordingly the present , invention provides methods and means for the identification and use of modulators of this unique activity of BACE2 to suppress A.beta. production. The compounds identified using the methods and means provided herein may be used as potential candidates for the treatment of Alzheimer's disease and other neurological diseases.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 27, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended June 27, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 27, 2023.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.