Compounds and methods for modulating bacterial functions
CA 2411512 A1 · Owner: Suzuki, Kazushi · Inventors: Suzuki, Kazushi; Romeo, Tony; Wang, Xin
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
There is provided a method of reducing biofilm formation by biofilm-forming bacterial cell such as E. coli, Salmonella or Klebsiella cells. CsrA activity , levels in the cell may be modulated to impact biofilm formation and glycogen metabolism. CsrA levels may be modulated by modulating the expression of csrB RNA and UvrY and Bar A gene products. By increasing levels of csrB BarA or SdiA in a , bacterial, cell or increasing the rate of UvrY phosphorylation one can increase the , levels of, active UvrY in the cell. There is also provided a modulator of CsrA activity in a, bacteria comprising a nucleotide sequence containing the sequence element CAGGAUG.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 19, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 19, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 19, 2024.
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Timeline
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.