Induction of tolerance to a therapeutic polypeptide
CA 2411186 A1 · Owner: Herzog, Roland W. · Inventors: High, Katherine A.; Arruda, Valder R.; Herzog, Roland W.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Liver-directed gene transfer can induce immunological tolerance to a polypeptide, associated with the expression of a therapeutic nucleic acid Hepatic expression of a, transgene induces tolerance to the expression product of the transgene or to , post-translational, product related to transgene expression thereby ameliorating or eliminating , the immune responses associated with gene therapy and protein replacement respectively, independent of, the genetic background of the subject.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed November 5, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended November 5, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 5, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.