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Colchinol derivatives as angiogenesis inhibitors

CA 2410562 A1 · Owner: Arnould, Jean Claude · Inventors: Arnould, Jean Claude

CIPO record

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Abstract From the Canadian patent

The invention related to colchinol derivatives of the formula (I): Wherein: R1, R2 and R3 are each independently hydroxy phosphoryloxy (-OPO3H2), C1-, 4alkoxy or an in vivo hydrolysable ester of hydroxy with the proviso that at , least 2 of R1 R2 and R3 are C1-4alkoxy; A is -CO-, -C(O)O- -CON(R8)- , (wherein R8 is hydrogen, C1-4alkyl C1-3alkoxyC1-3alkyl, aminoC1-3alkyl or hydroxyC1-3alkyl); a is an integer from 1 to 4 inclusive; Ra and Rb are independently selected from hydrogen, hydroxy and amino; B is -O- -CO-, N(R9)CO-, -CON(R9)-, -N(R9)C(O)O- -N(R9)CON(R10)-, -N(R9)SO2-, -SO2N(R9)- or a direct single blond (wherein R9 and R10 are independently selected from hydrogen, C1-4alkyl, …

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed July 4, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended July 4, 2021.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 4, 2023.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledJuly 4, 2001
GrantedNo grant recorded
Term endedJuly 4, 2021
Patent numberCA 2410562 A1
Classification (IPC)C07D295/18 +2 more

Timeline

Timeline From CIPO dates

2002200420062008201020122014201620182020Application filedJuly 4, 2001Term endedJuly 4, 2021

Sources & verification

Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.