Method and form of a drug delivery device,such as encapsulating a toxic core within a non-toxic region in an oral dosage form

Abstract From the Canadian patent

A drug delivery device such as an oral dosage form (ODF) with a toxic or potent core encapsulated by a non-toxic region. The non-toxic region may be a region including multiple layers, coatings shells, and combinations thereof, which provides protection to and isolation from the toxic or potent core. The drug in the toxic or potent core is incorporated into the dosage form via for , example, three-dimensional printing as a solution, solubilization or , suspension of solid particles in liquid rather than by the more conventional , handling and compressing of dry powder. This minimizes the likelihood of creating airborne particles of the toxic drug during manufacturing hence , controlling …