Compositions and methods for delivery of a molecule into a cell
CA 2407570 A1 · Owner: The Regents Of The University Of California · Inventors: Schubert, Ulrich; Greene, Warner C.; Sherman, Michael P.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Provided is a composition comprising a Vpr polypeptide conjugated to a therapeutic molecule. Preferably, the Vpr comprises synthetic Vpr. The therapeutic molecule can comprise any molecule capable of being conjugated to Vpr or a fragment thereof, including a polypeptide a polynucleotide, and/or a , toxin. The invention additionally provides a method for delivering a molecule into a cell. The method comprises contacting the cell with a conjugate comprising a Vpr polypeptide conjugated to the molecule. The invention further provides a method for modulating the expression of a transgene in a cell a , method for killing a target cell population in a subject a method for , increasing the …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 23, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 23, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 23, 2023.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.