A process for the preparation of epothilone analogs and intermediates
CA 2404212 C · Owner: Guo, Zhenrong · Inventors: Thornton, John E.; Li, Wen Sen; Swaminathan, Shankar
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to a process for the preparation of epothilone analogs by initially forming novel ring-opened epothilones and carrying out a macrolactamization reaction thereon. The subject process is amenable to being carried out in a single reaction vessel without isolation of the intermediate compound and provides at least about a three-fold increase in yield over prior processes for preparing the desired epothilone analogs.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 12, 2001 and granted May 1, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended March 12, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 12, 2023.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.