Therapeutic peptides having a motif that binds specifically to non-acetylated h3 and h4 histones for cancer therapy
CA 2404100 A1 · Owner: Galvez, Alfredo F. · Inventors: Galvez, Alfredo F.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention describes a composition of matter comprising a conserved structural motif that allows the targeting and binding of a chromatin binding protein to non-acetylated histone H3 and H4 and prevents their acetylation. This invention is responsible for the anti-carcinogenic property of a chromatin binding peptide isolated from soybean seed. This structural motif is found in a highly conserved manner in other chromatin-binding proteins from different species. Modifications to this structural motif such as fusions to other proteins with functional motifs and amino acid substitutions have potential therapeutic applications and can be developed as an in vivo gene …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 23, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 23, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 23, 2023.
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Timeline
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.