Simple and efficient hydrazinolysis of c-10 and c-13 ester functionalities of taxanes to obtain 10-dab iii
CA 2403227 A1 · Owner: Mcchesney, James D. · Inventors: Rodenburg, Douglas L.; Mcchesney, James D.; Chander, Madhavi C.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to a process for producing 10-deacetyl baccatin III from an acidic solution containing a spectrum of taxanes which comprises , contacting the acidic solution with a hydrazine hydrate thereby to convert , into 10-deacetyl baccatin III some taxanes in the solution that are not 10deacetyl baccatin III. The present invention also provides a process for producing 10-deacetyl baccatin III from an acidic biomass extract which , comprises contacting the biomass extract with an appropriate solvent thereby to form an acidic solution, and contacting the solution with a hydrazine hydrate thereby to cleave the ester functionality of a taxane solute having an ester …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 16, 2001. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 16, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 16, 2023.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.