Method of preparing alkylated salicylamides via a dicarboxylate intermediate
CA 2402719 C · Owner: Bernadino, Joseph N. · Inventors: O'Toole, Doris C.; Bernadino, Joseph N.; Bay, William E.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to a method of preparing an alkylated salicylamide from , a protected and activated salicylamide via a dicarboxylated salicylamide intermediate. The present invention also relates to dicarboxylic salicylamide delivery , agent compounds for the delivery of active agents. Methods of administration are , provided as well. A non limitative example of a particularly preferred dicarboxylated , salicylamide may be represented by the formula: (see above formula) , where R1, R2, R3 and R4 are independently hydrogen; halogen; C1-C4 alkoxy optionally substituted with -OH or F; -OH; C1-C4 alkyl optionally substituted , with -OH , or F; -COOH; -OC(O)CH3; -SO3H; …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 21, 2001 and granted March 20, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended March 21, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 21, 2023.
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Sources & verification
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.