Nucleic acid formulations comprising poly-amino acids for gene delivery and methods of use
CA 2401327 C · Owner: Fewell, Jason G. · Inventors: Maclaughlin, Fiona; Nicol, Francois; Smith, Louis C.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Disclosed is a formulation for delivery of a nucleic acid molecule to a cell, comprising a nucleic acid and an anionic polymer selected from the group consisting of poly glutamic acid, poly aspartic acid, a copolymer consisting of glutamic acid and aspartic acid, and salts thereof wherein , the anionic polymer is non-encapsulating and enhances delivery of the nucleic acid to the cell compared to delivery of the nucleic acid without the polymer, and wherein the formulation does not contain a, cationic polymer. Examples of the anionic polymer includes poly-amino acids such as poly-L-glutamic acid, poly-D-glutamic acid, poly-L-aspartic acid poly-D-aspartic , acid, and salts thereof.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 2, 2001 and granted May 6, 2014. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended March 2, 2021.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 2, 2023.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.